ELISA CDC42BPB anti-

Quantity :100µL Clone Number: Aliases:CDC42 binding protein kinase beta antibody; CDC42-binding protein kinase beta antibody; CDC42BPB antibody; DMPK like beta antibody; DMPK-like beta antibody; KIAA1124 antibody; MRCK beta antibody; MRCKB_ antibody; Myotonic dystrophy kinase related CDC42 binding kinase beta antibody; Myotonic dystrophy kinase-related CDC42-binding kinase beta antibody; Myotonic dystrophy protein kinase like beta antibody; Myotonic dystrophy protein kinase-like beta antibody; Serine/threonine protein kinase MRCK beta antibody; Serine/threonine-protein kinase MRCK beta antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y5S2 Immunogen:SyntheQuantityd peptide derived from internal of MRCKB. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regµLation of cytoskeleton reorganization and cell migration. RegµLates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/mLC2. In concert with MYO18A and LURAP1, is involved in modµLating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. Nakajima D., DNA Res. 9:99-106(2002). Olsen J.V., Cell 127:635-648(2006). Hirosawa M., DNA Res. 6:329-336(1999). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDC42BPB Research Areas:Signal transduction