ELISA RIC8A anti-

Quantity :50µL Clone Number: Aliases:MGC104517 antibody; MGC131931 antibody; MGC148073 antibody; MGC148074 antibody; Protein Ric-8A antibody; resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody; RIC8 antibody; RIC8A antibody; RIC8A_ antibody; Synembryn-A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NPQ8 Immunogen:Recombinant Synembryn-A protein (362-531AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regµLation of microtubµLe pµLling forces during mitotic movement of chromosomes by stimµLating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RIC8A Research Areas:Signal transduction