ELISA CDK6 anti-

Quantity :50µL Clone Number: Aliases:CDK 6 antibody; CDK6 antibody; CDK6_ antibody; Cell division protein kinase 6 antibody; Crk 2 antibody; Crk2 antibody; Cyclin dependent kinase 6 antibody; Cyclin-dependent kinase 6 antibody; MCPH12 antibody; MGC59692 antibody; p40 antibody; PLSTIRE antibody; Serine/threonine protein kinase PLSTIRE antibody; Serine/threonine-protein kinase PLSTIRE antibody; STQTL11 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q00534 Immunogen:Fusion protein of CDK6 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50 Background:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regµLators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regµLatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regµLate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regµLated in some types of cancer. MµLtiple alternatively spliced variants, encoding the same protein, have been identified. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDK6 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology