ELISA BRD7 Antibody, HRP

Quantity :50µg Clone Number: Aliases:75 kDa bromodomain protein antibody; BP75 antibody; BRD 7 antibody; BRD7 antibody; BRD7_ antibody; Bromodomain containing 7 antibody; bromodomain containing protein 7 antibody; Bromodomain-containing protein 7 antibody; CELTIX 1 antibody; CELTIX1 antibody; NAG4 antibody; Protein CELTIX-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NPI1 Immunogen:Recombinant Bromodomain-containing protein 7 protein (601-651AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regµLating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-regµLates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regµLates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BRD7 Research Areas:Epigenetics and Nuclear Signaling; Cell biology