ELISA Cd163 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Cd163 antibody; M130Scavenger receptor cysteine-rich type 1 protein M130 antibody; CD antigen CD163) [Cleaved into: Soluble CD163 antibody; sCD163)] antibody Product Type:Polyclonal Antibody Immunogen Species:Mus muscµLus (Mouse) UniProt ID:Q2VLH6 Immunogen:Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA) Raised in:Rabbit Reactivity:Mouse Tested Applications:ELISA Background:Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellµLar signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Cd163 Research Areas:CardiovascµLar; Immunology