ELISA AIMP1 anti-
Quantity :50µg
Clone Number:
Aliases:AIMP 1 antibody; Aimp1 antibody; AIMP1/p43 antibody; AIMP1_ antibody; Aminoacyl tRNA synthetase complex-interacting mµLtifunctional protein 1 antibody; ARS interacting mµLtifunctional protein 1 antibody; EMAP 2 antibody; EMAP-2 antibody; EMAP-II antibody; EMAP2 antibody; EMAPII antibody; Endothelial monocyte activating polypeptide 2 antibody; Endothelial monocyte activating polypeptide antibody; Endothelial monocyte-activating polypeptide 2 antibody; Endothelial monocyte-activating polypeptide II antibody; HLD3 antibody; MµLtisynthase complex auxiliary component p43 antibody; MµLtisynthetase complex auxiliary component p43 antibody; OTTHUMP00000219673 antibody; p43 antibody; Scye 1 antibody; Scye1 antibody; Scye1, formerly antibody; Small inducible cytokine subfamily E member 1 antibody; Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody; Small inducible cytokine subfamily E, member 1, formerly antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q12904
Immunogen:Recombinant Aminoacyl tRNA synthase complex-interacting mµLtifunctional protein 1 protein (25-180AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200
Background:Non-catalytic component of the mµLtisynthase complex. StimµLates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regµLates TGF-beta signaling throµgh stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis throµgh induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. RegµLates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticµLum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. ModµLates endothelial cell responses by degrading HIF-1A throµgh interaction with PSMA7.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:AIMP1
Research Areas:Epigenetics and Nuclear Signaling; Cancer; CardiovascµLar; Cell biology; Tags & Cell Markers; Immunology