ELISA ALKBH1 anti-
Quantity :50µL
Clone Number:
Aliases:ABH antibody; ABH1 antibody; alkB antibody; alkB homolog 1 histone H2A dioxygenase antibody; AlkB; alkylation repair homolog 1 (E. coli) antibody; ALKB1_ antibody; ALKBH antibody; ALKBH1 antibody; Alkylated DNA repair protein alkB homolog 1 antibody; Alkylation repair homolog 1 antibody; Alkylation repair; alkB homolog antibody; Alpha-ketoglutarate-dependent dioxygenase ABH1 antibody; DNA lyase ABH1 antibody; DNA oxidative demethylase ALKBH1 antibody; hABH antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q13686
Immunogen:Recombinant Alkylated DNA repair protein alkB homolog 1 protein (110-389AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecµLar oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ALKBH1
Research Areas:Epigenetics and Nuclear Signaling