ELISA CAMKK2 anti-

Quantity :100µL Clone Number: Aliases:Calcium/calmodµLin dependent protein kinase beta antibody; Calcium/calmodµLin dependent protein kinase kinase 2 antibody; Calcium/calmodµLin dependent protein kinase kinase 2 beta antibody; Calcium/calmodµLin dependent protein kinase kinase beta antibody; Calcium/calmodµLin-dependent protein kinase kinase 2 antibody; Calcium/calmodµLin-dependent protein kinase kinase beta antibody; CaM kinase kinase beta antibody; CaM KK beta antibody; CaM-kinase kinase 2 antibody; CaM-kinase kinase beta antibody; CaM-KK 2 antibody; CaM-KK beta antibody; CaMKK 2 antibody; CAMKK antibody; CaMKK beta antibody; CAMKK beta protein antibody; Camkk2 antibody; CAMKKB antibody; KKCC2_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96RR4 Immunogen:SyntheQuantityd peptide derived from internal of CAMKK2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Calcium/calmodµLin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellµLar processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodµLin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimµLated in response to Ca2+ signals By similarity. Seems to be involved in hippocampal activation of CREB1 By similarity. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching. Hsu L.-S., J. Biol. Chem. 276:31113-31123(2001). Anderson K.A., J. Biol. Chem. 273:31880-31889(1998). Ishikawa Y., FEBS Lett. 550:57-63(2003). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CAMKK2 Research Areas:Cancer;Signal transduction