ELISA CASP14 anti-

Quantity :50µL Clone Number: Aliases:Apoptosis related cysteine protease antibody; CASP 14 antibody; CASP-14 antibody; CASP14 antibody; Caspase 14 apoptosis related cysteine protease antibody; Caspase 14 precursor antibody; Caspase-14 subunit p10 antibody; Caspase14 antibody; CASPE_ antibody; MGC119078 antibody; MGC119079 antibody; MICE antibody; Mini ICE antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P31944 Immunogen:Fusion protein of CASP14 Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CASP14 Research Areas:Cell biology