ELISA BRE anti-

Quantity :50µL Clone Number: Aliases:6030405P19Rik antibody; AI429776 antibody; B830038C02Rik antibody; Brain and reproductive organ expressed (TNFRSF1A modµLator) antibody; brain and reproductive organ expressed protein antibody; Brain and reproductive organ-expressed protein antibody; BRCA1 A complex subunit BRE antibody; BRCA1-A complex subunit BRE antibody; BRCA1/BRCA2 containing complex subunit 4 antibody; BRCA1/BRCA2 containing complex subunit 45 antibody; BRCA1/BRCA2-containing complex subunit 45 antibody; BRCC4 antibody; BRCC45 antibody; bre antibody; BRE_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NXR7 Immunogen:Fusion protein of BRE Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellµLar juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregµLates TNFa-induced activation of NFkB and may play a role in homeostasis or cellµLar differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medµLla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BABAM2 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology