ELISA C2orf40 anti-

Quantity :50µL Clone Number: Aliases:AµgN_ antibody; Aµgurin antibody; C2orf40 antibody; Esophageal cancer-related gene 4 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H1Z8 Immunogen:Synthetic peptide of C2orf40 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:ECRG4 (esophageal cancer-related gene 4 protein), also known as aµgurin or C2orf40, is a 148 amino acid secreted protein. Belonging to the aµgurin family, ECRG4 is thoµght to be a hormone. It has also been sµggested that ECRG4 may act as a tumor suppressor. The gene that encodes ECRG4 maps to chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8% of the genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr m syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that chromosome 2 is the resµLt of an ancient fusion of two ancestral chromosomes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:C2orf40 Research Areas:Others