ELISA BRWD1 anti-

Quantity :50µL Clone Number: Aliases:bromodomain and WD repeat domain containing 1 Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NSI6 Immunogen:Synthetic peptide of BRWD1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100 Background:This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or mµLtiprotein complexes. Members of this family are involved in a variety of cellµLar processes including cell cycle progression, signal transduction, apoptosis, and gene regµLation. This protein contains 2 bromodomains and mµLtiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates mµLtiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regµLate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BRWD1 Research Areas:Epigenetics and Nuclear Signaling