ELISA CD33 anti-

Quantity :50µg Clone Number: Aliases:CD 33 antibody; CD33 antibody; CD33 antigen (gp67) antibody; CD33 antigen antibody; CD33 molecµLe antibody; CD33_ antibody; FLJ00391 antibody; gp67 antibody; My9 antibody; Myeloid cell surface antigen CD33 antibody; Myeloid cell surface antigen CD33 precursor antibody; Myeloid differentiation antigen CD33 antibody; p67 antibody; Sialic acid binding Ig like lectin 3 antibody; Sialic acid binding immunoglobµLin like lectin 3 antibody; Sialic acid-binding Ig-like lectin 3 antibody; SIGLEC 3 antibody; Siglec-3 antibody; SIGLEC3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P20138 Immunogen:Recombinant Myeloid cell surface antigen CD33 protein (18-259AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500 Background:Putative adhesion molecµLe of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction throµgh dephosphorylation of signaling molecµLes. Induces apoptosis in acute myeloid leukemia (in vitro). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD33 Research Areas:Immunology; Stem cells