ELISA CAV1 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_ antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q03135 Immunogen:Peptide sequence from Caveolin-1 protein (26-43AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regµLate their activity (By similarity). Involved in the costimµLatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regµLate CTNNB1-mediated signaling throµgh the Wnt pathway. Negatively regµLates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (PubMed: 25893292). Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed: 19262564). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CAV1 Research Areas:Cancer; CardiovascµLar; Tags & Cell Markers; Metabolism; Signal transduction