ELISA CALD1 anti-

Quantity :50µL Clone Number: Aliases:CAD antibody; CALD 1 antibody; CALD1 antibody; CALD1_ antibody; Caldesmon 1 antibody; Caldesmon 1 Isoform 1 antibody; Caldesmon 1 Isoform 2 antibody; Caldesmon 1 Isoform 3 antibody; Caldesmon 1 Isoform 4 antibody; Caldesmon 1 Isoform 5 antibody; Caldesmon antibody; Caldesmon1 antibody; CDM antibody; H CAD antibody; HCAD antibody; L CAD antibody; LCAD antibody; MGC21352 antibody; NAG22 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q05682 Immunogen:Recombinant Caldesmon protein (1-240AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Actin- and myosin-binding protein implicated in the regµLation of actomyosin interactions in smooth muscle and nonmuscle cells (coµLd act as a bridge between myosin and actin filaments). StimµLates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodµLin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecµLes of tropomyosin and with calmodµLin. Also play an essential role during cellµLar mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CALD1 Research Areas:CardiovascµLar; Signal transduction