ELISA BVES anti-

Quantity :50µL Clone Number: Aliases:Blood vessel epicardial substance antibody; Bves antibody; hBVES antibody; MGC42413 antibody; POP 1 antibody; POP1 antibody; POPD1_ antibody; POPDC 1 antibody; POPDC1 antibody; Popeye domain containing 1 antibody; Popeye domain containing protein 1 antibody; Popeye domain-containing protein 1 antibody; Popeye protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8NE79 Immunogen:Recombinant Blood vessel epicardial substance protein (241-360AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200 Background:Cell adhesion molecµLe involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regµLation of the tight junction (TJ) paracellµLar permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicµLar transport and recycling of different receptor molecµLes throµgh its interaction with VAMP3. Plays a role in the regµLation of cell shape and movement by modµLating the Rho-family GTPase activity throµgh its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regµLation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regµLatory function in heart rate dynamics mediated, at least in part, throµgh cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BVES Research Areas:Signal transduction