ELISA CD146 Monoclonal anti-

Quantity :50µL Clone Number:4D10C7 Aliases:Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecµLe) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146), MCAM, MUC18 Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:P43121 Immunogen:Recombinant Cell surface glycoprotein MUC18 protein (50-646AA) Raised in:Mouse Reactivity: Tested Applications:ELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200 Background:Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellµLar junctions in vascµLar tissue. Its expression may allow melanoma cells to interact with cellµLar elements of the vascµLar system, thereby enhancing hematogeneous tumor spread. CoµLd be an adhesion molecµLe active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellµLar calcium concentration. Clonality:Monoclonal Isotype:IgG2a Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD146 Research Areas:Immunology