ELISA BCR anti-

Quantity :50µL Clone Number: Aliases:ALL antibody; bcr antibody; BCR/ABL FUSION GENE, INCLUDED antibody; BCR/FGFR1 chimera protein antibody; BCR/FGFR1 FUSION GENE, INCLUDED antibody; BCR/PDGFRA FUSION GENE, INCLUDED antibody; BCR_ antibody; BCR1 antibody; Breakpoint cluster region antibody; Breakpoint cluster region protein antibody; CmL antibody; D22S11 antibody; D22S662 antibody; FGFR1/BCR chimera protein antibody; PHL antibody; Renal carcinoma antigen NY-REN-26 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P11274 Immunogen:Synthetic peptide of BCR Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Althoµgh the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCR Research Areas:Cancer;Signal transduction